IUBMB Enzyme Nomenclature

EC 1.14.99.21

Accepted name: Latia-luciferin monooxygenase (demethylating)

Reaction: Latia luciferin + reduced acceptor + 2 O2 = oxidized Latia luciferin + CO2 + formate + acceptor + H2O +

Glossary Latia-luciferin = (E)-2-methyl-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-1-en-1-yl formate

Other name(s): luciferase (Latia luciferin); Latia luciferin monooxygenase (demethylating)

Systematic name: Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)

Comments: A flavoprotein. Latia is a bioluminescent mollusc. The reaction possibly involves two enzymes, an oxygenase followed by a monooxygenase for the actual light-emitting step.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 62213-54-1

References:

1. Shimomura, O. and Johnson, F.H. The structure of Latia luciferin. Biochemistry 7 (1968) 1734-1738. [PMID: 5650377]

2. Shimomura, O., Johnson, F.H. and Kohama, Y. Reactions involved in bioluminescence systems of limpet (Latia neritoides) and luminous bacteria. Proc. Natl. Acad. Sci. USA 69 (1972) 2086-2089. [PMID: 4506078]

[EC 1.14.99.21 created 1976, modified 1982]


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