Reaction: vinorine + [reduced NADPHhemoprotein reductase] + O2 = vomilenine + [oxidized NADPHhemoprotein reductase] + H2O
For diagram of reaction click here.
Systematic name: vinorine,[reduced NADPHhemoprotein reductase]:oxygen oxidoreductase (21α-hydroxylating)
Comments: A cytochrome P-450 (heme-thiolate) protein from the plant Rauvolfia serpentina. Forms a stage in the biosynthesis of the indole alkaloid ajmaline.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Falkenhagen, H. and Stöckligt, J. Enzymatic biosynthesis of vomilenine, a key intermediate of the ajmaline pathway, catalysed by a novel cytochrome P-450-dependent enzyme from plant cell cultures of Rauwolfia serpentina. Z. Naturforsch. C: Biosci. 50 (1995) 45-53.