Reaction: L-lysine + O2 = 5-aminopentanamide + CO2 + H2O
Other name(s): lysine oxygenase; lysine monooxygenase; L-lysine-2-monooxygenase
Systematic name: L-lysine:oxygen 2-oxidoreductase (decarboxylating)
Comments: A flavoprotein (FAD). Also acts on other diamino acids.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9031-22-5
References:
1. Nakazawa, T., Hori, K. and Hayaishi, O. Studies on monooxygenases. V. Manifestation of amino acid oxidase activity by L-lysine monooxygenase. J. Biol. Chem. 247 (1972) 3439-3444. [PMID: 4624115]
2. Takeda, H. and Hayaishi, O. Crystalline L-lysine oxygenase. J. Biol. Chem. 241 (1966) 2733-2736. [PMID: 5911646]
3. Takeda, H., Yamamoto, S., Kojima, Y. and Hayaishi, O. Studies on monooxygenases. I. General properties of crystalline L-lysine monooxygenase. J. Biol. Chem. 244 (1969) 2935-2941. [PMID: 5772467]