Reaction: 2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced acceptor
Other name(s): ketogluconate dehydrogenase; α-ketogluconate dehydrogenase; 2-keto-D-gluconate dehydrogenase; 2-oxogluconate dehydrogenase
Systematic name: 2-dehydro-D-gluconate:acceptor 2-oxidoreductase
Comments: A flavoprotein.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9028-82-4
1. Datta, A.G. and Katznelson, H. The oxidation of 2-ketogluconate by a partially purified enzyme from Acetobacter melanogenum. Arch. Biochem. Biophys. 65 (1956) 576-578.
2. Shinagawa, E. and Ameyama, M. 2-Keto-D-gluconate dehydrogenase from Gluconobacter melanogenus, membrane-bound. Methods Enzymol. 89 (1982) 194-198.