IUBMB Enzyme Nomenclature

EC 1.1.1.414

Accepted name: L-galactonate 5-dehydrogenase

Reaction: L-galactonate + NAD+ = D-tagaturonate + NADH + H+

Other name(s): lgoD (gene name); lgaC (gene name)

Systematic name: L-galactonate:NAD+ 5-oxidoreductase

Comments: The enzyme, reported from the human gut bacteria Escherichia coli and Bacteroides vulgatus, participates in an L-galactonate degradation pathway.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Cooper, R.A. The pathway for L-galactonate catabolism in Escherichia coli K-12. FEBS Lett. 103 (1979) 216-220. [PMID: 381020]

2. Kuivanen, J. and Richard, P. The yjjN of E. coli codes for an L-galactonate dehydrogenase and can be used for quantification of L-galactonate and L-gulonate. Appl. Biochem. Biotechnol. 173 (2014) 1829-1835. [PMID: 24861318]

3. Hobbs, M.E., Williams, H.J., Hillerich, B., Almo, S.C. and Raushel, F.M. L-Galactose metabolism in Bacteroides vulgatus from the human gut microbiota. Biochemistry 53 (2014) 4661-4670. [PMID: 24963813]

[EC 1.1.1.414 created 2018]


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