Reaction: 10-hydroxy-α-humulene + NAD+ = zerumbone + NADH + H+
For diagram of reaction click here.
Other name(s): ZSD1
Systematic name: 10-hydroxy-α-humulene:NAD+ oxidoreductase
Comments: The enzyme was cloned from shampoo ginger, Zingiber zerumbet.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Okamoto, S., Yu, F., Harada, H., Okajima, T., Hattan, J., Misawa, N. and Utsumi, R. A short-chain dehydrogenase involved in terpene metabolism from Zingiber zerumbet. FEBS J. 278 (2011) 2892-2900. [PMID: 21668645]