Research
Antibody

Specificity: Human; Applications: IHC

Description and applications

Mouse antibody against Human Mast cell marker (Subclass: IgG1)

MCG25 is useful for mast cell identification in immunological reactions and hypersensitivity diseases e.g. allergy and asthma. The antigen is found in granule components of mast cells and may also be found intracytoplasmically in human mature small enterocytes, liver parenchymal cells and kidney proximal tubule epithelial cells.


Applications:  IHC

Commercially available at Abcam. Collaboration with Rimmer E.F.

Publications

Rimmer et al. 1987. Clin Exp Immunol. 68(3):712-8. PMID: 3308221.
Rimmer et al. 1984. J Clin Pathol. 37(11):1249-55. PMID: 6389604.

Keywords

Mast cell marker, osteoclasts, marker, antibody, immunohistochemistry

Prof Michael Horton

Previously at Barts hospital

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