Research
Antibody

Specificity: Human; Applications: IHC ELISA WB

Description and applications

1-  Mouse antibody against Human Keratin 6 (Subclass: IgG1 kappa)

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratin 9 to 23) and on type II kerating (1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 6,16 and 17 are expressed in suprabasasl keratinocytes of wounded epidermis. Keratin 6 is found in acrosyringeal keratinocyes in normal skin. LHK6 is a very good marker for hyperproliferative keratinocytes.     

Applications:  IHC ELISA WB

Commercially available at Leica Microsystems

Publications

Toivola et al. 2002. Mol Biol Cell. 13(6):1857-70. PMID: 12058054.  
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.
Machesney et al. 1998. Am J Pathol. 152(5):1133-41. PMID: 9588880.

Keywords

Antibody, Keratin 6, epithelium, tissue differentiation, keratinocyte

Prof Irene Leigh

Previously at Blizard Institute

Want access?

Get in touch with the Business Development Office smd-qmbusiness@qmul.ac.uk