Research
Antibody

Specificity: Human; Applications: FACS IHC IF WB

Description and applications

1-  Mouse antibody against Human Keratin 7 (Subclass: IgG1)

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19.

Applications:  FACS IHC IF WB

Commercially available at EMD Millipore

Publications

Sato et al. 2005. Blood. 106(2):428-35. PMID: 15797992.
Sato et al. 2003. Development. 130(22):5519-32. PMID: 14530297.  
Markey et al. 1991. J Invest Dermatol. 97(5):763-70. PMID: 1717607.  
Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-58.PMID: 2417515.

Keywords

Antibody, Keratin 7, keratinocyte, sebaceous glands, sweat glands

Prof Irene Leigh

Previously at Blizard Institute

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