Research
Antibody

Specificity: Human; Applications: ELISA FACS IHC IF IP WB

Description and applications

Mouse antibody against human and mouse AF10 (Subclass: IgG2b)

Human and Mouse AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available.

Applications:  ELISA IHC IP WB

Commercially available at Abcore

Keywords

acute myeloid leukaemia, antibody, AF10

Prof Bryan D Young

Barts Cancer Institute

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