Mouse antibody against Bovine, Human, Mouse and Rat Keratin 15 (Subclass: IgG2a kappa)
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes.
Commercially available at EMD Millipore
Applications: ELISA FACS IHC IF IP WB
Inoue et al. 2009. Lab Invest. 89(8):844-56. PMID: 19506554.
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.
Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.
Previously at Blizard Institute
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