Research
Antibody

Specificity: Bovine, Human, Mouse and Rat; Applications: ELISA FACS IHC IF IP WB

Description and applications

Mouse antibody against Bovine, Human, Mouse and Rat Keratin 15 (Subclass: IgG2a kappa)

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes.

Commercially available at  EMD Millipore

Applications: ELISA FACS IHC IF IP WB

Publications

Inoue et al. 2009. Lab Invest. 89(8):844-56. PMID: 19506554.
Porter et al. 2000. Lab Invest. 80(11):1701-10. PMID: 11092530.  
Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. PMID: 10084315.

Keywords

Antibody, Keratin 15, epithelium, tissue differentiation, keratinocyte

Prof Irene Leigh

Previously at Blizard Institute

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