Research
Vector

Oncolytic Vaccinia Virus (Lister strain) deleted with the Thymidine Kinase gene and armed with murine IL-10 gene.

Description and applications

Oncolytic Vaccinia Virus (Lister strain) deleted with the Thymidine Kinase gene and armed with murine IL-10 gene.

VVL∆TK-IL10 has strong potential as an anti-tumor therapeutic for solid tumours

Publications

http://clincancerres.aacrjournals.org/content/early/2014/11/21/1078-0432.CCR-14-0464.abstract

Keywords

Viral Gene therapy; Cancer immunotherapy; oncolytic virus

Prof Yaohe Wang

Barts Cancer Institute

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