Research
Small molecule

Anti-Angiogenic Peptide which exploits a novel pathway (not VEGF)

Description and applications

QM107 exploits a novel pathway (not VEGF). QM107 has shown to cause an 80% reduction in sprouting in murine aortic ring model, a 35% decrease in HUVEC cell migration and micro-capillary formation and a 50% decrease in angiogenesis in Matrigel plug assays. PK data excellent.

Publications

www.ncbi.nlm.nih.gov/pubmed/21813734

Keywords

Angiogenesis, peptide

Dr James Whiteford

William Harvey Institute

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