A novel ScFv antibody highly specific for human arthritic synovial microvasculature

Description and applications

A stable recombinant antibody with intrinsic red fluorescent properties for qualitative and quantitative immunofluorescence analysis. Genetically assembled rather than covalently linked incorporating the fluorophore as a bridging scaffold confers superior properties. Expression and purification steps can be monitored without the need for sophisticated detection equipment. The platform allows panels of coloured antibodies to generate both diagnostic and therapeutic molecules.

Dr. Constantino Pitzalis

Institute of Dentistry

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