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Our Studies

The PCTU is involved in a number of projects, which are at varying stages and led by a variety of investigators. 

For further information please click on the research titles below: 

Study Acronym CRESCENDO study page [DOC 73KB]                                                   
Study Title                                      Development of a screening tool to predict the success of laparoscopic surgery for women                                                                                                 
PCTU Ref P263               
Chief Investigator Dr Elizabeth Ball, Queen Mary University of London
Funder/Funding Stream NIHR Research for Patient Benefit                                                                                                                     
Sponsor Barts NHS Trust

 

Study Acronym ESTEEM                                                      
Study Title                           Effect of simple, targeted diet in pregnant women with metabolic risk factors on pre-eclamp sia: A randomised trial
PCTU Ref P138
Chief Investigator  Professor Shakila Thangaratinam, Queen Mary University of London
Funder/Funding Stream Barts and The London Charity                                                                                                                                               
Sponsor Barts NHS Trust

 

Study Acronym  ERA                                                                                 
Study Title Effectiveness of group arts therapy for diagnostically heterogeneous patients in mental health services   
PCTU Ref                            P262
Chief Investigators  Catherine Carr, Queen Mary University of LondonProfessor Stefan Priebe, Queen Mary University of London
Funder/Funding Stream NIHR Health Technology Assessment                                                                                                                      
Sponsor East London NHS Foundation Trust

 

Study Acronym Eye-2-i                                                               
Study Title                                                                                         The Early Youth Engagement in first episode psychosis (EYE-2) study: pragmatic cluster randomised controlled trial of implementation, effectiveness & cost effectiveness of a team-based motivational engagement intervention to improve engagement                                                                   
PCTU Ref             P252                              
Chief Investigator  Dr Kathy Greenwood, University of Sussex
Funder/Funding Stream NIHR Health Services & Delivery Research                                                                                                                     
Sponsor Sussex Partnership NHS Foundation Trust 

 

Study Acronym FLO-ELA                                                         
Study Title                             FLuid Optimisation in Emergency LAparotomy. Open, multi-centre,
randomised controlled trial of cardiac output -guided haemodynamic therapy compared
to usual care in patients undergoing emergency bowel surgery                                              
PCTU Ref P217
Chief Investigator  Dr Mark Edwards, University Hospital Southampton NHS Foundation Trust
Funder/Funding Stream     NIHR Health Technology Assessment                                                                                                                                      
Sponsor University Hospital Southampton NHS Foundation Trust

  

Study Acronym MEMPHIS                                                
Study Title                              A smartphone app using psychological approaches for women with chronic pelvic pain: a randomised feasibility trial
PCTU Ref P156
Chief Investigator  Dr Elizabeth Ball, Queen Mary University of London
Funder/Funding Stream Research for Patient Benefit                                                                                                                                                    
Sponsor Barts Health NHS Trust

 

Study Acronym OPTIMISE II                                                               
Study Title                             OPTimisation of cardIovascular Management to Improve Surgical outcomE II                                                                             
PCTU Ref             P221                          
Chief Investigator  Professor Rupert Pearse, Queen Mary University of London
Funder/Funding Stream Edwards Lifesciences                                                                                                                     
Sponsor Barts Health NHS Trust

 

Study Acronym OSIRIS                                                              
Study Title                              Optimising Shared Decision Making for High Risk Major surgery Surgery                                                                           
PCTU Ref             P249                       
Chief Investigator  Professor Rupert Pearse, Queen Mary University of London
Funder/Funding Stream NIHR Programme Grant 
Sponsor Barts Health NHS Trust

 

Study Acronym PIMS                                                             
Study Title                                                                                A multicentre interventional comparative randomised controlled clinical trial comparing face-down positioning, with an inactive face-forward position on the outcome of surgery for large macular holesPositioning in Macular hole Surgery (Positioning in Macular hole Surgery)
PCTU Ref             P110                              
Chief Investigator  Professor James Bainbridge, University College London
Funder/Funding Stream NIHR Research for Patient Benefit                                                                                                                   
Sponsor Moorfield's Eye Hospital NHS Trust

 

Study Acronym SUBSoNIC                                                                    
Study Title                          Randomised Double-Blind Efficacy and Mechanism Study Of Sacral Neuromodulation In Adults With Faecal Incontince     
PCTU Ref P178
Chief Investigator  Professor Charles Knowles, Queen Mary University of London
Funder/Funding Stream NIHR Efficacy and Mechanism Evaluation (EME) Programme/ Medtronic Inc                                  
Sponsor Barts NHS Trust

 

Study Acronym TANDEM                                                               
Study Title                                  A tailored, psychological intervention for mild to moderate anxiety or depression in people with chronic obstructive pulmonary disease(COPD)
PCTU Ref P159
Chief Investigator  Professor Stephanie Taylor, Queen Mary University of London
Funder/Funding Stream   NIHR Health Technology Assessment                                                                                                                      
Sponsor Barts NHS Trust

 

Study Acronym VidiKIDS                                                            
Study Title                            Trial of vitamin D supplementation to prevent acquisition of latent tuberculosis infection in schoolchildren
PCTU Ref P186
Chief Investigator  Professor Adrian Martineau, Queen Mary University of London
Funder/Funding Stream Medical Research Council (MRC)                                                                                                                                    
Sponsor Barts NHS Trust

 

Study Acronym VidiKIDS NCD - Substudy                                                          
Study Title                            Trial of vitamin D supplementation to prevent acquisition of latent tuberculosis infection in schoolchildren
PCTU Ref P274
Chief Investigator  Professor Adrian Martineau, Queen Mary University of London
Funder/Funding Stream Medical Research Council (MRC)                                                                                                                                    
Sponsor Barts NHS Trust

 

Programmes

Study Acronym                          CapaCiTY                                                            
Study Title                        Development of a UK evidence-based pathway for the management of chronic constipation in adults                                                     
PCTU Ref                                  P127
Chief Investigator  Professor Charles Knowles, Queen Mary University of London
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor Barts NHS Trust

 

Study Acronym  EMPOWER                                                    
Study Title                                                   EMPOWER: Enabling and Motivating People (with a Personality Disorder) in Occupation, Wellbeing, Education and Responsibility                                                                                
PCTU Ref P257
Chief Investigator  Dr Janet Feigenbaum, North East London NHS Foundation Trust
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor North East London NHS Foundation Trust

 

Study Acronym ENRICH                                                              
Study Title                                                                  Enhanced discharge from inpatient to community mental health care (ENRICH): a programme of applied research to manualise, pilot and trial a Peer Worker intervention                                                                                
PCTU Ref P154
Chief Investigator  Dr Steve Gillard, St George's, University of London
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor St George’s Healthcare NHS Trust

  

Study Acronym                                                  

IMP2ART
Study Title                                Implementing supported asthma self-management in routine clinical care:  designing, refining, piloting and evaluating clinical and cost-effectiveness of a whole systems implementation strategy                    
PCTU Ref P243
Chief Investigator  Dr Hilary Pinnock, University of Edinburgh
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor NHS Canterbury and Coastal CCG 

 

Study Acronym NEON
Study Title                                                Personal experience as a recovery resource in severe mental illness: Narrative Experiences ONline (NEON) Programme                                                                                        
PCTU Ref P227
Chief Investigator  Professor Mike Slade, University of Nottingham
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor Nottinghamshire Healthcare NHS Foundation Trust 

 

Study Acronym       REACH
Study Title                                  The REACH Pregnancy Programme (Research for Equitable Antenatal Care and Health)                                                                                               
PCTU Ref P123
Chief Investigator   Professor Angela Harden, University of East London
Funder/Funding Stream                 NIHR Programme Grant for Applied Research
Sponsor University of East London 

 

Study Acronym SCENE
Study Title                                                 Improving quality of life and health outcomes of patients with psychosis through a new structured intervention for expanding social networks                                                      
PCTU Ref P206
Chief Investigator  Dr. Domenico Giacco, Queen Mary University of London
Funder/Funding Stream NIHR Programme Grant for Applied Research
Sponsor East London NHS Foundation Trust

 

Study Acronym

 STOP
Study Title Optimising pharmacist-based treatment for smoking cessation                                                                
PCTU Ref P027
Chief Investigator Professor Robert Walton, Queen Mary University of London
Funder/Funding Stream NIHR Programme Grant for Applied Research
Sponsor Barts NHS Trust

 

Study Acronym             SURECAN                                                                                                                                                   
Study Title SUrvivors Rehabilitation Evaluation after CANcer                                                                
PCTU Ref P228
Chief Investigator Professor Stephanie Taylor, Queen Mary University of London                                                        
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor Barts NHS Trust

 

Study Acronym                 TACK
Study Title                                            Tackling chronic depression - Adapting and testing a technology supported, patient-centred and solution focused intervention (DIALOG+) in primary care     
PCTU Ref P207
Chief Investigator  Dr Vicky Bird, Queen Mary University of London
Funder/Funding Stream                    NIHR Programme Grant for Applied Research
Sponsor East London NHS Foundation Trust

 

Study Acronym                            VOLUME                                                                
Study Title             Volunteering in Mental Health Care for People with Psychosis                                                                                                     
PCTU Ref P090
Chief Investigator  Professor Stefan Priebe, Queen Mary University of London
Funder/Funding Stream     NIHR Programme Grant for Applied Research
Sponsor East London NHS Foundation Trust


Other

Study Acronym                                CHILL                                                             
Study Title             A cohort study to evaluate Ultra Low Emission Zone                                                                                                                              
PCTU Ref P242
Chief Investigator  Professor Chris Griffiths, Queen Mary University of London
Funder/Funding Stream     NIHR Public Health Research
Sponsor Barts NHS Trust

 

Study Acronym                 IPPIC     
Study Title                                                                                  Accuracy of clinical characteristics, biochemical and ultrasound markers in the prediction of preeclampsia: an Individual Patient Data (IPD) Meta-analysis                                                                                                                                                                                          
PCTU Ref P177
Chief Investigator  Professor Shakila Thangaratinam, Queen Mary University of London
Funder/Funding Stream     NIHR Health Technology Asssessment
Sponsor Barts NHS Trust

 

Study Acronym                 i-WIP                                                            
Study Title                                                                                   Effects of weight management interventions on maternal and fetal outcomes in pregnancy: Individual patient data (IPD) meta analysis of randomised trials and model based economic evaluation                                                                                                                   
PCTU Ref P105
Chief Investigator 

Professor Shakila Thangaratinam, Queen Mary University of London
Funder/Funding Stream     NIHR Health Technology Assessment
Sponsor Barts NHS Trust

 

Study Acronym                          PROMISe                                                            
Study Title             Patient Reported Outcome MeasureS using electronic informed consent and data capture – developing methods and infrastructure              
PCTU Ref P265
Chief Investigator 
Dr Richard Hooper, Queen Mary University of London
Professor Charles Knowles, Queen Mary University of London
Funder/Funding Stream     NIHR CTU Support Funding
Sponsor Barts NHS Trust

 

Study Acronym                                PROMETHEUS                                              
Study Title     Routinely embedding recruitment and retention interventions within randomised controlled trials                                                                                        
PCTU Ref P268
Chief Investigator  Professor David Torgerson, University of York
Funder/Funding Stream     MRC Methodology Research Panel
Sponsor University of York 
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