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Centre for Translational Bioinformatics

Katriona Goldmann, MPhys, MSc

Katriona

PhD Student

Centre: Centre for Translational Bioinformatics and the Centre for Experimental Medicine and Rheumatology

Email: k.goldmann@qmul.ac.uk

Profile

Katriona completed an undergraduate degree in Astrophysics at the University of Edinburgh in 2015. This was followed by a masters degree in Biomedical Engineering at the Strathclyde University. She joined the William Harvey Research Institute in 2017 as a Junior Bioinformatician working collaboratively between the Centre for Experimental Medicine and Rheumatology and the Centre for Translational Bioinformatics.

In 2018 Katriona started her PhD exploring multi-omic data integration in autoimmune diseases. She combines data from multiple biological sources including the genome, transcriptome and proteome to try and identify drivers of disease and move towards personalised or stratified medicine. She also focuses on creating interactive computational tools to analyse big biological data online using Shiny, R, and Plotly.

 

Supervisors

  • Dr Myles Lewis
  • Dr Michael Barnes

Research

Publications

    JavaException: java.lang.IllegalArgumentException: Illegal character in query at index 101: http://www.researchpublications.qmul.ac.uk/publications/GetAllStaffOutputXML.action?staffids=Cherlin, Svetlana, Myles J. Lewis, Darren Plant, Nisha Nair, Katriona Goldmann, Evan Tzanis, Michael R. Barnes et al.  ”Investigation of genetically regulated gene expression and response totreatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatmentresponse.” Annals of the Rheumatic Diseases (2020).  doi:  10.1136/annrheumdis-2020-217204\nRivellese, F., F. Humby, S. Bugatti, L. Fossati-Jimack, H. Rizvi, D. Lucchesi, G. Lliso-Ribera... K. Goldmann, M. J. Lewis, A. Manzo, M. Bombardieri, C. Pitzalis.  ”B cell synovitis and clinicalphenotypes in rheumatoid arthritis:  relationship to disease stages and drug exposure.” Arthritis &Rheumatology 72, no.  5 (2020):  714-725.  doi:  10.1002/art.41184\nJohn, Christopher R., David Watson, Dominic Russ, Katriona Goldmann, Michael Ehrenstein, Costantino Pitzalis, Myles Lewis, and Michael Barnes.  ”M3C: Monte Carlo reference-based consensusclustering.” Scientific reports 10, no.  1 (2020):  1-14.doi:  10.1038/s41598-020-58766-1\nPucino, Valentina, Michelangelo Certo, Vinay Bulusu, Danilo Cucchi, Katriona Goldmann, Elena Pontarini, Robert Haas et al.  ”lactate Buildup at the site of chronic inflammation Promotes Disease byinducing cD4+ T cell Metabolic rewiring.” Cell metabolism 30, no.  6 (2019):  1055-1074.doi:10.1016/j.cmet.2019.10.004\nLewis, Myles J., Michael R. Barnes, Kevin Blighe, Katriona Goldmann, Sharmila Rana, Jason A. Hackney, Nandhini Ramamoorthi et al.  ”Molecular portraits of early rheumatoid arthritis identify clinicaland treatment response phenotypes.” Cell reports 28, no.  9 (2019):  2455-2470.doi:10.1016/j.celrep.2019.07.091\nBoutet, Marie-Astrid, Alessandra Nerviani, Gloria Lliso-Ribera, Davide Lucchesi, Edoardo Prediletto, Giulia Maria Ghirardi,Katriona Goldmann, Myles Lewis, and Costantino Pitzalis.  ”Interleukin-36family dysregulation drives joint inflammation and therapy response in psoriatic arthritis.” Rheumatology59, no.  4 (2020):  828-838.  doi:  10.1093/rheumatology/kez358\nEl Shikh, Mohey Eldin M., Riham El Sayed, Alessandra Nerviani, Katriona Goldmann, ..., Myles J. Journal ofAutoimmunity2019Lewis, and Costantino Pitzalis.  ”Extracellular traps and PAD4 released by macrophages inducecitrullination and auto-antibody production in autoimmune arthritis.” Journal of Autoimmunity 105(2019):  102297.  doi:  10.1016/j.jaut.2019.06.008&flatXML=Y