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Paediatric and Adolescent Gastro-Intestinal and Liver Diseases, Gastro-Intestinal Infections (ICMM937/945)

Module Co-ordinators:

Prof Nick Croft,

Prof Ian Sanderson,

This module serves as a thorough overview of gastrointestinal and liver diseases in children and adolescents and gastrointestinal infectious diseases.

The aims of this module are to provide understanding and knowledge of the common and unusual diseases of the gastrointestinal, hepato-biliary, pancreatic tracts in children and adolescents, and infectious diseases of the GI tract. There is a focus on the science and research underpinning the diseases

  • GI and liver preclinical sciences (e.g. embryology, anatomy, post natal development, physiology) and the abnormalities of this development.
  • Ethics and practicalities of research in children.
  • Normal and abnormal growth and puberty. Normal and abnormal nutrition.
  • Acute infective diarrhoea in children.
  • Chronic diarrhoea and enteropathy (Coeliac disease, etc)
  • Congenital chronic intractable diarrhoea
  • CF and the Gut, pancreatic insufficiency
  • Functional GI Diseases in children.
  • Food allergy and intolerance
  • Rectal bleeding including polyps syndromes
  • Inflammatory bowel disease, Adult versus paeds, growth and bones and enteral feeds. Clinical assessment of intestinal immunity
  • Cholestatic jaundice (the yellow baby). Hepatitis
  • Chronic liver disease and liver transplantation  in childhood
  • Malnutrition in children. Intestinal failure, short gut and small bowel transplantation
  • Indication and complications of parenteral nutrition. Feeding and swallowing difficulties in children (including oesophageal dysmotility, achalasia)
  • GI Infections and tropical gastroenterology: immunity against organisms, mucosal vaccines. Bacterial, protozoal and viral infections.

By the end of this module students should be able to:

  1. Describe common and unusual diseases of the gastrointestinal, hepatobiliary and pancreatic tracts in children and adolescents,
  2. Discuss the pathogenesis and management of infectious diseases of the gastrointestinal tract.
  3. Develop skills of enhanced clinical decision-making in this area

Pediatric GI Diseases (Kleinman, Goulet et al)

Pediatric GI and Liver Diseases (Wylie, Hyams)

One examination lasting 1 hour. This module exam is worth 60% of the mark for the module, with the remaining 40% constituted by coursework, which will be set at the start of the module. The coursework assignment [essay] will have a maximum of 2000 words, or an oral presentation or a poster presentation to the examiner.


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