Blizard Institute - Barts and The London

Mrs Claire Chan



Telephone: 020 7882 6306


After completing a BSc degree in Statistics at University College London (2010-13), Claire completed a two-year National Institute for Health Research (NIHR) methods fellowship at the Pragmatic Clinical Trials Unit (PCTU). As part of the fellowship Claire gained an MSc degree in Medical Statistics at the London School of Hygiene and Tropical Medicine (2013-14). Claire now works as a Statistician in the PCTU, with current research interests in both pilot and feasibility studies and cluster randomised trials. In particular, Claire is part of the group who produced papers on definitions of pilot and feasibility studies and the CONSORT extension for external pilot trials. She has been involved in leading several workshops on these topics, and is also an Associate Editor of the Pilot and Feasibility Studies Journal. Claire also organises the annual cluster meeting on Current Developments in Cluster Randomised Trials and Stepped Wedge Designs, and led the creation of two websites designed to support researchers in the design, analysis, and reporting of cluster randomised trials and pilot and feasibility studies.




Karla Hemming, Kelly Carroll, Jennifer Thompson, Andrew Forbes, Monica Taljaard, The SW-CRT Review Group. Quality of stepped-wedge trial reporting can be reliably assessed using an updated CONSORT: crowd-sourcing systematic review. Journal of clinical epidemiology. 2019;107:77-88

Rosemary Townsend, Asma Khalil, Yaamini Premakumar, John Allotey,  Kym I.E. Snell, Claire Chan, Lucy C Chappell, Richard Hooper, Marcus Green, Ben W. Mol, Basky Thilaganathan, Shakila Thangaratinam. Accuracy of tests in the prediction of pre-eclampsia: Review of Reviews. Ultrasound in Obstetrics and Gynecology. 2018. doi: 10.1002/uog.20117

Claire L Chan, Clémence Leyrat, Sandra M Eldridge. Quality of reporting of pilot and feasibility cluster randomised trials: a systematic review. BMJ Open. 2017; 7:e016970. doi: 10.1136/bmjopen-2017-016970

John Allotey, Kym I. E. Snell, Claire Chan, Richard Hooper, Julie Dodds, Ewelina Rogozinska, Khalid S. Khan et al. and for the IPPIC Collaborative. External validation, update and development of prediction models for pre-eclampsia using an Individual Participant Data (IPD) meta-analysis: the International Prediction of Pregnancy Complication Network (IPPIC Pre-eclampsia) protocol. Diagnostic and Prognostic Research. 2017; 1:16

Eldridge SM, Chan CL, Campbell MJ, Bond CM, Hopewell S, Thabane L, Lancaster GA on behalf of the PAFS consensus group. Consort 2010 statement: extension to randomised pilot and feasibility trials. BMJ. 2016; 355: i5239

Eldridge SM, Chan CL, Campbell MJ, Bond CM, Hopewell S, Thabane L, Lancaster GA on behalf of the PAFS consensus group. Consort 2010 statement: extension to randomised pilot and feasibility trials. Pilot and Feasibility Studies. 2016; 2(64)

MacInnes D, Kinane C, Parrott J, Mansfield J, Craig T, Eldridge S, Marsh I, Chan C, Hounsome N, Harrison G, Priebe S. A Pilot Cluster Randomised Trial to Assess the Effect of a Structured Communication Approach on Quality of Life in Secure Mental Health Settings: The Comquol Study. BMC Psychiatry. 2016; 16(355)

Lehana Thabane, Sally Hopewell, Sandra M Eldridge, Michael J Campbell, Gillian A Lancaster, Claire L Coleman, Christine M Bond. Methods and processes for development of a CONSORT extension for reporting pilot randomized controlled trials. Pilot and Feasibility Studies. 2016; 2(25)

Sandra M Eldridge, Gillian A Lancaster, Michael J Campbell, Lehana Thabane, Sally Hopewell, Claire L Coleman, Christine M Bond. Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework. PLoS ONE. 2016; 11(3)

Ayerbe L, González E, Gallo V, Coleman CL, Wragg A, Robson J. Clinical assessment of patients with chest pain; a systematic review of predictive tools. BMC Cardiovascular Disorders. 2016; 16:18

Díaz-Ordaz K, Kenward MG, Cohen A, Coleman CL, Eldridge S. Are missing data adequately handled in cluster randomised trials? A systematic review and guidelines. Clinical Trials. 2014; 11(5):590-600

Northrop PJ, Coleman CL. Improved threshold diagnostic plots for extreme value analyses. Extremes. 2014; 17(2):289-303