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Blizard Institute - Barts and The London

Dr Patrick Pallier, PhD

Lecturer in Neuroscience

Centre: Centre for Neuroscience, Surgery and Trauma

Email: p.pallier@qmul.ac.uk
Telephone: 020 7882 2284

Profile

Patrick Pallier did his PhD at INSERM in Bordeaux, France. He then worked as a post-doctoral researcher in the School of Psychology at the University of St Andrews, and in the Department of Pharmacology at Cambridge University, before joining Prof. Adina Michael-Titus and Prof. John Priestley at Queen Mary University of London, in the Centre for Neuroscience, Surgery and Trauma in the Blizard Institute, where he became a Lecturer in Neuroscience. His research is multidisciplinary and translational, and uses a wide array of in vitro and in vivo techniques. It focuses on the characterization and development of novel therapeutic approaches to protect and repair the brain or the spinal cord after trauma, delay ageing, or prevent the occurrence of neurodegenerative conditions. He is a Fellow of The Higher Education Academy.

Teaching

Undergraduate and Post-graduate taught courses:

  • MBBS: Brain and Behaviour module (module co-lead Year 1, lecturer, tutor for Problem-Based Learning, Year 1 and 2)
  • Medicine Graduate Entry Programme: Brain and Behaviour module (module co-lead and lecturer)
  • Intercalated BSc Neuroscience: Disconnected Pathways module and Brain and Mind module (lecturer)
  • BSc (Hon) Neuroscience: Perspectives on Brain Disorders module (lecturer); Systems Neuroscience (lecturer)
  • MSc Neuroscience and Translational Medicine: Chronic pain and epilepsy (module co-lead and lecturer); Neuro-oncology (module co-lead); Research projects (module co-lead)

Laboratory-based and Non-laboratory-based project Supervisor: BSc (Hon) Neuroscience; BSc in Biomedical Sciences; MSc Neuroscience and Translational Medicine; SSC

Academic advisor for BSc (Hon) Neuroscience (Year 1 to 3) and MSc Neuroscience and Translational Medicine students

Research

Research Interests:

Neuroprotection and neurorepair; spinal cord injury; brain injury; ageing and neurodegeneration

 

Recent and ongoing research projects:

  • Development of specialised nutritional interventions in neurotrauma
  • Development of fatty acid emulsions for use in acute neuroprotection in spinal cord injury
  • Development of new compounds with neuroprotective and neurotrophic properties
  • Protecting the brain vasculature after trauma
  • White matter ageing

 

Group members:

  • Isabell Nessel (Research Assistant)
  • Tatenda Mutshiya (Research Technician)

Publications

Key Publications

Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV, Dalli J, Tremoleda JL, Michael-Titus AT (2019) A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice. Journal of Neurotrauma vol. 37, (1) 66-79. doi: 10.1089/neu.2019.6420.

Gushchina S, Pryce G, Yip PK, Wu D, Pallier PN, Giovannoni G, Baker D and Bo X (2018) Increased expression of colony-stimulating factor-1 in mouse spinal cord with experimental autoimmune encephalomyelitis correlates with microglial activation and neuronal loss. Glia vol. 66, (10) 2108-2125. doi: 10.1002/glia.23464.

Pallier PN, Poddighe L, Zbarsky V, Kostusiak M, Choudhury R, Hart T, Burguillos MA, Musbahi O, Groenendijk M, Sijben JW, deWilde MC, Quartu M, Priestley JV and Michael-Titus AT (2015) A nutrient combination designed to enhance synapse formation and function improves outcome in experimental spinal cord injury. Neurobiology of Disease vol. 82, 504-515.

Ward RE, Huang W, Kostusiak M, Pallier PN, Michael-Titus AT and Priestley JV (2014) A characterization of white matter pathology following spinal cord compression injury in the rat. Neuroscience vol. 260, 227-239.

All Publications

Supervision

  • Eleanor Sams (PhD student)