Blizard Institute - Barts and The London

Dr Orli Thau Zuchman, BPT, MSc, PhD

Senior Research Fellow, Clinical Research Fellow

Centre: Centre for Neuroscience, Surgery and Trauma

Email: o.thau-zuchman@qmul.ac.uk
Telephone: 020 7882 2282

Profile

I explore immediate and delayed inflammatory responses induced by Traumatic Brain Injury, specifically the impact of therapeutic agents on recovery. I develop TBI models for assessing the efficacy of these agents. My approach draws both from my background as a neuroscientist and my clinical experience as a neuro-rehabilitation physiotherapist. 

LinkedIn: /orli-thau-zuchman-neuroscience

Research

Publications

Key Publications

Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV, Dalli J, Tremoleda JL, Michael-Titus AT. A Single Injection of Docosahexaenoic Acid Induces a Pro-Resolving Lipid Mediator Profile in the Injured Tissue and a Long-Lasting Reduction in Neurological Deficit after Traumatic Brain Injury in Mice. J Neurotrauma. 2019 Sep 6. doi: 10.1089/neu.2019.6420.

Thau-Zuchman O, Gomes RN, Dyall SC, Davis M, Priestley JV, Groenendijk M, DE Wilde M, Lopez-Tremoleda J, Michael-Titus AT. Brain phospholipid precursors administered post-injury reduce tissue damage and improve neurological outcome in experimental traumatic brain injury. J Neurotrauma. 2019 Jan 1;36(1):25-42. doi: 10.1089/neu.2017.5579.

J. L. Tremoleda, O. Thau-Zuchman, M. Davies, J. Foster, I. Khan, K. C. Vadivelu, P. K. Yip, J. Sosabowski, W. Trigg, A. T. Michael-Titus. In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [18F] GE-180 and effect of docosahexaenoic acid. Eur J Nucl Med Mol Imaging. 2016 Aug 2016; 43(9):1710-22.

Thau-Zuchman ODocosahexaenoic acid and traumatic brain injury. Lipid Technology. March 2015; 27(3).

All Publications