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Simon Coppack


Reader in Metabolic Medicine

Telephone: 020 7882 2369


Between October 1991-October 1992 I worked with Drs MD Jensen and JM Miles in Dr RA Rizza's Endocrine Research Unit of the Mayo Clinic, Rochester, Minnesota, U.S.A. The research focussed on developing HPLC and isotope tracer methodology for kinetics of triglyceride, fatty acid and glycerol metabolism in adipose tissue and in circulating lipoproteins (especially triglyceride-rich lipoproteins). These methods have since been applied to studies of the control of lipolysis. During subsequent visits to the U.S.A. between 1993 and 2001, I visited Dr RR Wolfe (University of Texas Medical Center, Galveston) Dr S Klein (Washington University School of Medicine, St Louis) and Dr G Eisenhofer, National Institutes of Health, Bethesda as well as returning to the Mayo Clinic. These later transatlantic visits were used to study catecholamine kinetics and microdialysis of adipose tissue interstitial fluid.

Personal Research Awards:

1977: Medical Research Council, Intercalated BSc at King College London & UCL
1988: Nuffield Foundation, Travelling Fellowship (to visit Copenhagen)
1988-1990: Medical Research Council, Training Fellowship (in Oxford)
1991: Frewin Prize (Oxford Region Postgraduate Committee, for work in Oxford)
1991-1992: Fulbright Commission, Scholarship (to work at Mayo Clinic)
1991-1992: Mayo Foundation, Visiting Scientist (for work at Mayo Clinic)
1992: Oxford Regional Health Authority, Visiting Scientist (to work at Mayo Clinic)
1993: Medical Research Society Travelling Fellowship (to work at University of Texas)
1993: Mayo Foundation, Visiting Faculty
1994: Shriners' Visiting Fellowship (to visit University of Texas)
1995: R.D. Lawrence Lectureship (British Diabetic Association)
1996: King's Fund Travel Grant (to visit Washington University, St Louis)

Research Coordinator East London Obesity Service (HUH & QMUL)


I am a clinical academic with an active clinic practice at Barts Health NHS Trust and Homerton University Hospital.

My research interests are in the field of lipids, obesity, insulin resistance, non-insulin dependent diabetes, and nutritional fluxes.


Teaching to medical students year 2, 3 and 5 including PBLs, lectures and clinical teaching.

Chief Internal Examiner MBBS Part 6b

Lead for Diabetes sections of Endocrinology & Diabetes MSc.


Research Interests:

Obesity, adipose tissue, insulin resistance

Recent and ongoing research projects:

  • Member of Project Management Committee, EGIR RISC study.
  • Currently undertaking collaborative studies into body composition and appetite in relation to obesity


Mohamed-Ali V, et al. Subcutaneous adipose tissue secretes interleukin-6 but not tumour necrosis factor-α in vivo. J Clin Endocrinol Metab 1997;82:4196-4200

Yudkin JS et al. C-reactive protein in healthy subjects - associations with obesity, insulin resistance and endothelial dysfunction. Arterioscler Thromb Vasc Biol 1999;19:972-978

Ferrannini E et al. Insulin resistance, insulin response and obesity as indicators of metabolic risk. J Clin Endocrinol Metab. 2007;92:2885-2892

Vasileiou AM et al, Oedema in obesity, role of structural lymphatic abnormalities. Int J Obes. 2011;35:1247-1250


View all Simon Coppack's Research Publications at:

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