Dr Weiwei Jin, PhD
Postdoctoral Research Assistant
Centre: Centre for Genomics and Child Health
Weiwei has completed a BEng and an MEng in Mechanical Engineering at Chiba University, Japan. Her bachelor's thesis involved 1-D computational modelling of haemodynamic, while her Master's thesis focused on coupling the autonomic nervous system with a 1-D/0-D haemodynamic model. During her Master's, she also conducted a project on optimising coronary artery surgery using 3-D modelling in collaboration with medical doctors from Chiba University Hospital, Japan. After obtaining her Master's degree, she worked in the Center for Preventive Medical Sciences at Chiba University, Japan, for six months. During the six months, she evaluated statistical analysis methods for the dietary patterns and PCB contamination in pregnant women and their children. Then, she did her PhD at King's College London on investigating cardiovascular function using in silico methods, including computational blood flow modelling and machine learning. Her PhD work consists of three pasts: 1) investigate a common test for assessing endothelial dysfunction, flow-mediated dilation; 2) systematic comparison of haemodynamics on diseased arterial models between one-dimensional and either three-dimensional simulation or in vitro experiment; 3) using statistic and machine learning methods to identify indices reflect cardiovascular functions. She is currently working at the Centre for Genomics and Child Health to discover drugs to treat glioblastoma.
Weiwei is currently working on drug discovery for glioblastoma, a type of brain tumour, using infomation derived from both the tumour cells and healthy neural cells.
W Jin, P Chowienczyk, J Alastruey. An in silico simulation of flow-mediated dilation reveals that blood pressure and other factors may influence the response independent of endothelial function. American Journal of Physiology - Heart and Circulatory Physiology, 318:H1337-H1345, 2020
W Jin, M Otake, A Eguchi, K Sakurai, H Nakaoka, M Watanabe, E Todaka, C Mori. Dietary habits and cooking methods could reduce avoidable exposure to PCBs in maternal and cord sera. Scientific reports, 7:17357, 2017
W Jin, F Liang and H Liu. Hemodynamic response to exercise in supine and standing attitudes: an integrated model. Journal of Biomechanical Science and Engineering, 11:15-00523, 2016