Blizard Institute - Barts and The London

Dr Richard Hooper, PhD


Reader in Medical Statistics

Telephone: 020 7882 7324


Richard has had a 25-year career in health services research as a medical statistician, and currently conducts research at the forefront of innovation in the design of randomised evaluations of health technologies, including stepped wedge and other novel approaches to cluster-randomised trials. His published work on research methods has appeared in the BMJ, the International Journal of Epidemiology, and the Journal of Clinical Epidemiology, as well as Statistics in Medicine, and Statistical Methods in Medical Research. He has given invited talks at international conferences of the International Society for Clinical Biostatistics, Royal Statistical Society, and Society for Clinical Trials. He belongs to an international network of excellence in innovations in cluster randomised clinical trial methods, led from Monash University, Australia. He was recently awarded a Senior Fellowship by The Healthcare Improvement Studies (THIS) Institute, UK, to develop and promote innovation in clinical trial design as a key component of health improvement science. He is also a Senior Statistician at the Pragmatic Clinical Trials Unit – a UK registered Clinical Trials Unit specialising in evaluating interventions as they would be rolled out by health services – and co-leads the QMUL arm of Research Design Service London.



Topics for PhD supervision:

Optimal incomplete stepped wedge trials: staircase designs and beyond

Design of stepped wedge trials with continuous recruitment



Hooper R, Copas A. Stepped wedge trials with continuous recruitment require new ways of thinking. J Clin Epidemiol 2019;DOI:10.1016/j.jclinepi.2019.05.037

Hemming K, Taljaard M, McKenzie J, Hooper R, Copas A, et al. Reporting of stepped wedge cluster randomised trials: extension of the CONSORT 2010 statement with explanation and elaboration. BMJ 2018;363:k1614

Hooper R, Knowles C. Improving the efficiency of individually randomized clinical trials by staggering the introduction of the intervention. Stat Med 2018;DOI:10.1002/sim.7959

Hooper R, Forbes A, Hemming K, Takeda A, Beresford L. Analysis of cluster randomised trials with an assessment of outcome at baseline. BMJ 2018;360:k1121

Kasza J, Hemming K, Hooper R, Matthews JNS, Forbes AB. Impact of non-uniform correlation structure on sample size and power in multiple-period cluster randomised trials. Stat Methods Med Res 2017;DOI:10.1177/0962280217734981

Hooper R, Teerenstra S, de Hoop E, Eldridge E. Sample size calculation for stepped wedge and other longitudinal cluster randomised trials. Stat Med 2016;35(26):4718-4728

Hooper R, Bourke L. Cluster randomised trials with repeated cross sections: alternatives to parallel group designs. BMJ 2015;350:h2925

Hooper R, Bourke L. The dog-leg: an alternative to a cross-over design for pragmatic clinical trials in relatively stable populations. Int J Epidemiol 2014;43(3):930-936

View all Richard Hooper's Research Publications at: