Reaction: acetyl-CoA + N-hydroxyputrescine = N1-acetyl-N1-hydroxyputrescine + CoA
Glossary: N-hydroxyputrescine = N-hydroxybutane-1,4-diamine
Other name(s): fbsK (gene name)
Systematic name: acetyl-CoA:N-hydroxyputrescine N-acetyltransferase
Comments: The enzyme, characterized from the bacterium Acinetobacter baumannii ATCC 17978, participates in the biosynthesis of fimsbactin siderophores.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Proschak, A., Lubuta, P., Grun, P., Lohr, F., Wilharm, G., De Berardinis, V. and Bode, H.B. Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi. Chembiochem 14 (2013) 633-638. [PMID: 23456955]
2. Yang, J. and Wencewicz, T.A. In vitro reconstitution of fimsbactin biosynthesis from Acinetobacter baumannii. ACS Chem. Biol. 17 (2022) 2923-2935. [PMID: 36122366]