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Professor Mauro Perretti – Dean for Research and Research Impact

As Dean for Research at QMUL’s School of Medicine and Dentistry I know how important animals are in helping us to find better ways of preventing and treating the diseases that occur in both humans and animals.

In my own research into cardiovascular disease (diseases of the heart and blood vessels), rheumatism and arthritis, animal models have helped us to understand the role played by inflammation and the mechanisms involved in the onset of chronic inflammatory conditions.

We work mainly with mice to identify new cell receptors involved in the inflammation pathways so that we can design new drugs to target them.

We are acutely aware of the importance of assessing the relevance of our research to patients in the clinic. We want our research involving animals to translate quickly into new treatments for cardiovascular diseases, rheumatism and sepsis.

I, my team and all researchers at QMUL who work with animals share the same goals of adhering to the ‘3Rs’ – replacement, refinement and reduction – so that we use as few animals as possible to develop new therapies as quickly as possible for the benefit of human and animal health.

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