In School of Medicine and Dentistry Graduate School:
- Introduction
- Studentships and bursaries
See also:
- SMD Graduate School: Current Staff and Student
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Studentships and bursaries
- Epigenetic gene regulation and functional genomics of mammalian tissue-specific regulatory elements
- Nucleation and Crystallisation of leucite glass-ceramics for Biomedical applications
- See also
Epigenetic gene regulation and functional genomics of mammalian tissue-specific regulatory elements
This studentship within the Centre for Diabetes and Metabolic Medicine, ICMS, comes with a tax-free stipend of £14,350 per annum. Home/EU tuition fees will be paid by the Centre for Diabetes and Metabolic Medicine. Non-EU applicants will have to fund the difference between home and overseas tuition fees themselves, approximately £8000 per annum for a minimum of three years.
Supervisor: Vardhman Rakyan
Co-Supervisor: Dean Nizetic
We are looking for an enthusiastic graduate to work on a PhD project studying epigenetic gene regulation and functional genomics of mammalian tissue-specific regulatory elements. Epigenetic mechanisms modulate the activity of key tissue-specific regulatory elements, thereby permitting functional specialization of different cell types. However, identification of these tissue-specific regulatory elements has so far proven challenging. We have recently identified thousands of sites within the human and mouse genomes at which the DNA methylation profiles are tissue-specific, ie tissue-specific differentially methylated regions (tDMRs). Using a combination of high-density array profiling, bioinformatics and functional assays, we would now like to test the hypothesis that tDMRs are regulatory elements crucial for tissue-specific genome function in mammals.
Minimum requirements: Graduate with experience and interest in Molecular Genetics with at least an upper second class honours degree, or a lower second class honours degree with a Masters, is required for this project based at the Centre for Diabetes and Metabolic Medicine, located at the Institute of Cell and Molecular Sciences (ICMS), adjacent to The Royal London Hospital, Whitechapel.
These studies will involve functional genomics, genome-wide epigenetic and transcriptional profiling, molecular biology techniques and in vitro functional assays of regulatory elements.
Our laboratory is located in the brand new Institute of Cell and Molecular Sciences (ICMS) located in Whitechapel, adjacent to The Royal London Hospital where the graduate will have access to a wide variety of cutting-edge technologies and core facilities, as well as interaction with researchers across a wide range of biomedical research.
For an informal discussion, please contact the lead project supervisor:
Vardhman Rakyan
email: v.rakyan@qmul.ac.uk
To apply, please download the Postgraduate School of Medicine and Dentistry application form and return it to:
Helena Tkalez
Graduate School Office
The Admissions and Recruitment Office
Room CB02
Queens' Building
Mile End
E1 4NS
email: h.tkalez@qmul.ac.uk
We accept both postal and electronic applications.
Referees may email references directly to h.tkalez@qmul.ac.uk.
Please note that the closing date for applications is 12 August 2007.
Nucleation and Crystallisation of leucite glass-ceramics for Biomedical applications
This three-year studentship is funded directly by St Bartholomew’s and the Royal London Charitable foundation and comes with a tax-free stipend of £14,709 per annum and paid Home/EU tuition fees. Home/EU tuition fees will be paid by the Charitable Foundation. Non-EU applicants will have to fund the difference between home and overseas tuition fees themselves, approximately £8000 per annum for a minimum of three years.
Supervisor: Dr Mike Cattell
This is a unique opportunity to join a multidisciplinary team leading the field of Biomaterials research based in the Department of Biomaterials in Relation to Dentistry at Queen Mary’s Mile End campus. This will involve working on several sites and being exposed to many disciplines including Clinical Dentistry, Dental Technology and Material Science.
The project will explore the nucleation and crystallisation of selected aluminosilicate glasses in K2O-Al2O3-SiO2 system to synthesise, test and process high strength and low wear dental glass-ceramics, as part of a team. This may help to address the problems of brittle fracture and wear in all ceramic tooth replacements currently used in Restorative Dentistry. The student will gain experience in state of the art analytical and processing techniques and receive broad research training due to the many research groups they will interact with, including a working dental laboratory. The applicant will also have access to the Department of Materials, the Interdisciplinary Research Centre (Queen Mary) and the Dental Institute at the Whitechapel site.
This is an exciting and unique opportunity to work on a Biomaterials project with direct links to Clinical Dentistry and of industrial interest.
The applicant should have at least an upper second class honours degree in chemistry, material science, chemical engineering, or an allied subject and an interest in glass-ceramics. The start date for this project will be October 2007.
For an informal discussion, please contact the lead project supervisor:
Dr Mike Cattell
email: m.cattell@qmul.ac.uk
To apply, please download the Postgraduate School of Medicine and Dentistry application form and return it with a CV, two referees and a statement of interest to:
Helena Tkalez
Graduate School Office
The Admissions and Recruitment Office
Room CB02
Queens' Building
Mile End
E1 4NS
email: h.tkalez@qmul.ac.uk
as well as the principle project supervisor:
Dr Mike Cattell
Centre for Adult Oral Health
Barts and The London School of Medicine and Dentistry
Turner Street
Whitechapel
London
E1 2AD
email: m.cattell@qmul.ac.uk
We accept both postal and electronic applications.
Please note that the closing date for applications is 31 August 2007.