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A Practical Guide to Cluster Randomised Trials and Stepped Wedge Design


This course is based on the book 'A Practical Guide to Cluster Randomised Trials in Health Services Research' by Sandra Eldridge and Sally Kerry. The course incorporates developments in methodology since the book was written and, in particular, now includes substantial material on stepped wedge designs. The course is offered as a three day introductory course, a two day advanced course or as a comprehensive 5 day course combining the introductory and advanced courses.

CRT book cover

Full Course (Introduction + Advanced)  

(Course is close to closing - limited places available)

16th – 20th April 2018
Cost: ‘early bird’ rate £750 (available until 5th March), standard rate £900 (from 6th March – 5th April)

Introductory Course only

(Course is close to closing - limited places available)

16th – 18th April 2018
Cost: ‘early bird’ rate £500 (available until 5th March), standard rate £650 (from 6th March – 5th April)

Advanced course only

19th – 20th April 2018
Cost: ‘early bird’ rate £450 (available until 5th March), standard rate £600 (from 6th March – 5th April)
Location: Yvonne Carter Building, 58 Turner Street, E1 2AB
Availability: Limited places
Queen Mary staff qualify for a 33% discount on all courses
For further information contact

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Introductory course content

The introductory course covers:
  • Ethics
  • Recruitment
  • Piloting
  • Introduction to design
  • Reporting
  • Principles of health economics,
  • Avoiding bias and process evaluations
  • Introduction to analysis and sample size calculations.

Advanced course content

The advanced course covers
  • Systematic reviews,
  • Health economic analysis
  • Design
  • Analysis
  • Sample size calculations

Who this course is for

Anyone involved or with an interest in the design, conduct, analysis or reporting of a pragmatic trials in the academic or NHS sector. The course will be of interest to new principal investigators, statisticians, research nurses, PhD students, early career researchers and trial managers.

Course structure

The introductory course runs from Monday 16th April – Wednesday 18th April 2018 and A Practical Guide to Cluster Randomised Trials, Advanced Course follows the introductory course on Thursday 19th – Friday 20th April 2018.  Attendees can opt to attend the introductory course, the advanced course or the full 5 day course (introduction and advanced).

Course Team

Professor Sandra Eldridge                                                 

Sandra Eldridge is director of the Pragmatic Clinical Trials Unit. She has an international reputation in clinical trials particularly in cluster randomised trials, pragmatic trials and pilot and feasibility studies.  She has been involved in over 50 empirical studies, mostly trials, many cluster randomised and including pilot and feasibility studies. Sandra is an NIHR Senior Investigator, has sat on a number of funding panels for the National Institute of Health Research and is on the Council of the Royal Statistical Society and the Executive of the Society for Academic Primary Care.

Sally Kerry       

Sally Kerry joined the Pragmatic Clinical Trials Unit in September 2010 as a senior statistician, having worked at St. George’s for over 20 years. She has an interest in pragmatic trials in primary care and cluster randomised trials. She has written a number of methodological papers about the design and analysis of cluster trials and co-authored the book Presenting Statistics from Proposal to Publication with Professor Janet Peacock. She has been a principal trial investigator and is currently senior statistician on a number of PCTU studies including cluster trials.

Dr Richard Hooper 

Following his first degree in Maths in 1988 Richard studied statistics at Cambridge, and then joined a group of researchers in the Department of Academic Psychiatry who were studying mother-infant interactions and postnatal depression. Between 1993 and 1996 he also completed a part-time PhD in statistical pattern recognition. In 1996 he took up a Lecturer post at King's College London, transferring to Imperial College London in 2006 where he worked on the epidemiology of asthma and chronic obstructive pulmonary disease. In 2010 he moved to Queen Mary University of London, where he is a senior statistician at the Pragmatic Clinical Trials Unit and co-investigator on a portfolio of NIHR-funded studies supported by the Unit. He is also an academic lead for the East London and City arm of Research Design Service London. His current research interests are in clinical trials methods and innovative trial design.

Brennan Kahan

Brennan Kahan is a Lecturer in Medical Statistics, and is involved in the design and analysis of randomised controlled trials. He joined the Pragmatic Clinical Trials Unit in September, 2013 after spending almost 4 years at the MRC Clinical Trials Unit. He has experience working on applied cluster randomised trials, and has been involved in methodological research in clustered data and cluster-crossover trials.

Previous participants of this course have said:

 A very useful introduction to the key aspects of CRTs. Very well organised and useful course material”
 “CRTs are new to me so it was all useful”
 “Very enjoyable and informative”
 “Exercises were very worthwhile and helpful in consolidating theory. Really appreciated example articles as well. Thank you”

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