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Scientists find genetic variants influence a person’s response to statins

article News story: Scientists uncover stem cell behaviour of human bowel for the first time
7, August , 2014

For the first time, scientists have uncovered new information on how stem cells in the human bowel behave, revealing vital clues about the earliest stages in bowel cancer development and how we may begin to prevent it.

article News story: New brain tumour research Centre of Excellence is unveiled at QMUL
23, October , 2014

Patients, carers, scientists, clinicians and charities from across the UK will gather today for the launch of a ground-breaking new partnership between the charity Brain Tumour Research and Queen Mary University of London (QMUL) in collaboration with the UCL Institute of Neurology.

article News story: Research on a urine test for cervical cancer wins prize for QMUL academic clinical fellow
8, October , 2014

The Royal College of Obstetricians and Gynaecologists has awarded the Edgar Gentilli Prize to Dr Neha Pathak, a QMUL academic clinical fellow, for her research on a urine test for cervical cancer.

article News story: The UK’s first live-streamed surgical procedure takes place using Google Glass eyewear
23, May , 2014

Yesterday, for the first time in the UK, Queen Mary University of London (QMUL) and Barts Health NHS Trust broadcasted online a live surgical procedure using a pair of Google Glass eyewear.

article News story: Urine HPV test could offer alternative to conventional smear and improve screening uptake
17, September , 2014

A simple urine test for human papillomavirus (HPV) could offer a more acceptable, non-invasive alternative to the conventional cervical test and improve screening uptake, researchers from Queen Mary University of London have found.

article News story: Queen Mary University of London comments on first confidential enquiry into asthma deaths
6, May , 2014

Today the National Review of Asthma Deaths (NRAD) is calling for an end to complacency around asthma care so more can be done to save lives.

article News story: Four Queen Mary University of London scientists make Highly Cited Researchers 2014 List
15, July , 2014

Professor Mark Caulfield, Professor Jack Cuzick, Professor Trish Greenhalgh, and Professor Panos Deloukas have all been selected by Thomson Reuters for inclusion in their prestigious list of Highly Cited Researchers 2014

article News story: Scientists make major breakthrough in understanding leukaemia
14, August , 2014

Scientists from Queen Mary University of London (QMUL) have discovered mutations in genes that lead to childhood leukaemia of the acute lymphoblastic type – the most common childhood cancer in the world.

article News story: Dentistry ranked 1st and medicine 4th in UK by Complete University Guide
12, May , 2014

Queen Mary University of London (QMUL) has been rated first in the UK for Dentistry and fourth for Medicine in the Complete University Guide 2015 subject league tables, published today.

article News story: Mayor launches MedCity with £4.1m investment
8, April , 2014

The Mayor of London today launched MedCity, a partnership between the academic health science centres, UCLPartners – of which Queen Mary University of London is a founding member – King’s Health Partners and Imperial College, working with the Universities of Oxford and Cambridge and the Greater London Authority. Through collaborative effort, MedCity seeks to establish London and the South East of England as a world-leading centre for life sciences.

article News story: Campaign for real evidence-based medicine launches today
3, July , 2014

A campaign to put patient care at the centre of evidence-based medicine (EBM) is launched today by Professor Trish Greenhalgh, Public Health expert at Queen Mary University of London, at the BioMed Central’s Health Services Research conference at Kings’ College London.

article News story: QMUL scientists win Cancer Research UK prize
3, November , 2014

A team of researchers led by Queen Mary University of London (QMUL) have been awarded the 2014 Cancer Research UK Prize for Translational Cancer Research at the NCRI Cancer Conference in Liverpool.

article News story: NICE recommends brief counselling and as-needed nalmefene to help people with alcohol dependence
3, October , 2014

The drug nalmefene, which can help people dependent on alcohol cut down on the amount they drink, has been recommended in final draft guidance by the National Institute for Health and Care Excellence (NICE).

article News story: Faulty gene can delay or block puberty
25, March , 2014

Scientists from Queen Mary University of London have identified a new gene that may influence the timing of puberty, according to new research presented at today at the Society for Endocrinology annual BES conference. Until now, very little has been known about the genetic control of puberty.

article News story: The first UK medical school launches Google Glass technology in curriculum
29, October , 2014

Queen Mary University of London's Medical School – Barts and The London School of Medicine and Dentistry – is launching the ground-breaking use of Google Glass technology into its undergraduate curriculum, primarily within surgical teaching. This is the first of its kind outside of North America, having only been used by a small number of medical schools in the USA so far.

article News story: Half-term science fun at Centre of the Cell
1, May , 2014

Parents looking for something to entertain and educate budding scientists during the next half term can breathe easy, as Centre of the Cell in Whitechapel presents ‘Something in the Air’ – an interactive show about air pollution.

article News story: Google Glass in the operating theatre
11, July , 2014

By Shafi Ahmed, Associate Dean at Queen Mary University of London and Colorectal Cancer Lead at Barts Health NHS Trust

article News story: 1 in 6 women who have large tissue removal during colposcopy will have a premature birth
7, November , 2014

One in six women who have a large amount of tissue removed (15+mm) during colposcopy, to treat abnormal cells on the cervix, will go on to have a premature birth. This is double the number compared to those who have only a small amount removed – according to new findings from Queen Mary University of London.

article News story: Sixth-form students become cancer-research STARS
13, February , 2014

A-level students are gaining first-hand experience in cutting-edge cancer research, thanks to a new programme created at Queen Mary University of London’s Barts Cancer Institute (BCI).

article News story: THE World University Rankings: Medicine ranked in world top 50
1, October , 2014

Queen Mary University of London (QMUL) has been named amongst the top 50 universities in the world for Medicine in the influential Times Higher Education World University Rankings 2014-15.

article News story: Detection of Down syndrome during pregnancy improves for younger women
5, February , 2014

New figures from the National Down Syndrome Cytogenetic Register (NDSCR) based at Queen Mary University of London, reveal the proportion of Down syndrome cases diagnosed antenatally has increased in younger women.  Furthermore, Down syndrome diagnoses are occurring earlier in pregnancy for women of all ages. 

article News story: Scientists find genetic variants influence a person’s response to statins
28, October , 2014

A large analysis of over 40,000 individuals on statin treatment has identified two new genetic variants which influence how 'bad' cholesterol levels respond to statin therapy.

article News story: Scientists discover new mechanism which causes the spread of breast cancer
19, May , 2014

Scientists at Queen Mary University of London (QMUL) have uncovered a new mechanism which makes breast cancer cells move and invade the body, a discovery which could shed light on how to treat particularly aggressive forms of breast cancer and stop it spreading and recurring.         

article News story: What does canine anatomy have to do with clinical trials?
4, March , 2014

Queen Mary academics Dr Richard Hooper and Dr Liam Bourke put a new twist on a classic research design.

article News story: UK top 10 for QMUL in international science and medicine rankings
14, May , 2014

A league table measuring the scientific performance of some 750 universities worldwide rates Queen Mary University of London (QMUL) 9 th in the UK and 52 nd globally.

article News story: QMUL congratulates Professor Nick Lemoine on his NIHR Medical Director appointment
3, June , 2014

Queen Mary University of London (QMUL) is delighted to announce Professor Nick Lemoine, Director of QMUL’s Barts Cancer Institute, has been appointed to the new role of Medical Director at the National Institute for Health Research (NIHR) Clinical Research Network.

article News story: Aspirin: scientists believe cancer prevention benefits outweigh harms
5, August , 2014

New research from Queen Mary University of London (QMUL) reveals taking aspirin can significantly reduce the risk of developing – and dying from – the major cancers of the digestive tract, i.e. bowel, stomach and oesophageal cancer.

article News story: Vampires and monsters invade Centre of the Cell for Halloween
23, September , 2014

Vicious vampires, microscopic monsters, deadly diseases and an interactive snot show come to Centre of the Cell - Queen Mary University of London’s science education Pod in Whitechapel - this October.

article News story: Major grant for research into wound-healing
16, September , 2014

The UK’s leading medical charity for animal replacement research, the Dr Hadwen Trust (DHT), has awarded a major grant to Queen Mary University of London (QMUL) for research into healing chronic wounds, such as diabetes ulcers – a major healthcare concern in the UK.

article News story: Significant discovery could tackle spread of breast cancer
4, July , 2014

• New discovery reveals testing for molecule αvβ6 could identify a subset of breast cancer patients at high risk of their tumours spreading from the breast - and therefore twice as likely to die within five years• Combining αvβ6- antibody drug with breast cancer drug Herceptin ‘eradicated’ tumours in mice• Researchers are now looking at options to progress to a clinical trial in breast cancer patients

article News story: Health sector regulator using powers to reduce hospital and community services, warn experts
8, October , 2014

Licence conditions imposed by the health sector regulator, Monitor, on NHS foundation trusts in England will lead to a reduction in hospital community services under the guise of ‘continuity’, warn experts from Queen Mary University of London.  

article News story: Queen Mary University of London comments on Government handling of NHS Patient Data
8, April , 2014

Today the House of Commons Health Select Committee will hold an evidence session on Handling of NHS Patient Data. This will include hearing evidence from Kingsley Manning, Chair of the Health and Social Care Information Centre, and Max Jones, its Director of Information and Data Services.

article News story: QMUL hosts panel discussion on children and sport
25, November , 2014

Public health experts, doctors, professional sports players and parents are gathering at Queen Mary University of London (QMUL) on 27-28 November to debate issues around children and sport, including managing injury and increasing participation.

article News story: Public Health experts launch consultation on Draft Bill to restore the NHS
1, September , 2014

Leading public health experts have launched a consultation on a new Bill which aims to reverse the failings of the Health and Social Care Act 2012 and fully restore the National Health Service (NHS) in England as an accountable public service.

article News story: Risk of caesarean delivery 12% lower with induced labour
29, April , 2014

New research from Queen Mary University of London has found risk of caesarean delivery was 12% lower among women whose labour was induced, compared with women who were managed with a "wait-and-see" approach (expectant management). The findings are contrary to the popular view that inducing labour (starting labour artificially) increases risk of caesarean delivery.

article News story: New drug target can break down cancer's barrier against treatment
28, July , 2014

Scientists at Queen Mary University of London's Barts Cancer Institute have found that targeting a molecule in blood vessels can make cancer therapy significantly more effective, according to research published in Nature today (Monday 28 July),

article News story: Scientists discover link between skin diseases and Sudden Cardiac Death Syndrome
14, August , 2014

Scientists from Queen Mary University of London (QMUL) who specialise in genetics of the skin are investigating an unlikely link between skin disease and heart disease which will hopefully shed new light on why someone is predisposed to sudden cardiac death syndrome.

article News story: Queen Mary's Women's Health Research Unit launches ELLY appeal
12, March , 2014

Queen Mary University of London’s Women's Health Research Unit and Barts Health NHS Trust are collaborating with clinicians, researchers and volunteers to launch the East London International Women's Health appeal, also known as the ELLY Appeal.  

article News story: Report on e-cigarette dangers is misleading, say experts
5, September , 2014

World leading tobacco experts, including Professor Peter Hajek from Queen Mary University of London (QMUL), argue that a recently published World Health Organization (WHO)-commissioned review of evidence on e-cigarettes contains important errors, misinterpretations and misrepresentations.  

article News story: Screening helps prevent cervical cancer in older women
15, January , 2014

New research from Queen Mary University of London reveals women over the age of 50 who don’t attend cervical screening are six times more likely to be diagnosed with cervical cancer in later life.

article News story: Launch of £44m research fund to improve health outcomes for local people
26, February , 2014

A new collaboration of health researchers across the NHS, world-leading universities – including Queen Mary University of London – local authorities, clinical commissioning groups, industry and charities has launched today. The partnership will lead and join up innovative research tackling some of the major health challenges in the north Thames region.

article News story: Sense-ational school break science fun at Centre of the Cell
20, January , 2014

How can astronauts have secret conversations in space? Why do your feet go numb in cold water? And why does spicy food set your tongue on fire? Centre of the Cell will be answering these questions and more this half-term.

article News story: New approach to arthritis treatment could avoid serious side-effects
18, September , 2014

A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has been developed by researchers at Queen Mary University of London.

article News story: 750 million people worldwide suffering from severe gum disease
2, October , 2014

Hundreds of millions of people across the globe are suffering from severe gum infections, according to research led by Queen Mary University of London.

article News story: Queen Mary announces new research partnership with Brain Tumour Research
4, March , 2014

Queen Mary University of London is delighted to announce a ground-breaking new research partnership with UCL Institute of Neurology (under UCLPartners) and the charity Brain Tumour Research. The partnership begins a new chapter in long-term, sustainable and continuous research into brain tumours, the biggest cancer killer of children and adults under 40.

article News story: Current evidence suggests benefits of e-cigarettes outweigh harms
31, July , 2014

A major scientific review of available research on the use, content, and safety of e-cigarettes has concluded that – although long-term health effects of e-cigarette use are unknown – compared with conventional cigarettes they are likely to be much less harmful to users or bystanders.

article News story: New disease gene discovery sheds light on cause of bone marrow failure
6, February , 2014

New research from Queen Mary University of London has identified a novel genetic defect among patients with bone marrow failure, which could reveal its underlying cause.

article News story: Scientists discover 11 new genes affecting blood pressure
20, February , 2014

New research from Queen Mary University of London has discovered 11 new DNA sequence variants in genes influencing high blood pressure and heart disease.  

article News story: East London study looking into effects of Mediterranean diet in pregnancy launches today
13, June , 2014

Queen Mary University of London (QMUL) is today launching a new East London based study looking into the effects of a Mediterranean diet during pregnancy, and its ability to reduce pregnancy-related complications such as pre-eclampsia.

article News story: New study finds vulnerability to radicalisation is linked to depression
25, September , 2014

Members of the British Muslim community who are most at risk of radicalisation are more likely to have depression and be socially isolated, a pioneering research study led by Queen Mary University of London has found.

article News story: Online endocrinology degree shortlisted for national e-learning award
18, September , 2014

A Queen Mary University of London postgraduate course focusing on the science of hormone medicine has been shortlisted at this year’s national e-learning awards, in the category of ‘best online distance learning programme’.

article News story: QMUL signs head and neck cancer research agreement with Guiyang Medical University
12, June , 2014

Head and neck cancer experts at the Institute of Dentistry, Queen Mary University of London, have signed a joint agreement with their counterparts in China, to increase international exchanges and initiatives and raise standards of research in the field.

article News story: From Westminster to Whitechapel: Queen Mary takes part in Royal Society Pairing scheme
17, January , 2014

Professor Lord Winston – the distinguished medical scientist, television presenter and life peer – will be visiting Queen Mary University of London on January 17 2014 as part of a unique ‘pairing’ scheme run by the Royal Society, the UK national academy of science.

article News story: Study reveals text messages prevent one in six patients from failing to take medicine
5, December , 2014

Scientists from Queen Mary University of London have found text messaging prevents one in six patients from forgetting to take, or stopping, their prescribed medicines.

article News story: Large-scale HPV self-testing proves effective for screening cervical cancer
21, January , 2014

Self-testing for Human Papillomavirus (HPV) – the virus that causes cervical cancer – is as effective at detecting cancer as a conventional smear test (cytology screening) even when scaled up to test large populations.

article News story: Alternative Valentine's at Barts Pathology Museum
14, January , 2014

Lovesick hysterics, plundered hearts and the history of sexually transmitted diseases will be discussed in a series of February lectures at Barts Pathology Museum, part of Queen Mary University of London.

article News story: Scientific journals show little enforcement of animal research reporting guidelines
8, January , 2014

New findings from Queen Mary University of London reveal experimental flaws and a lack of transparent reporting is compromising the quality of animal studies and their potential to translate into the clinic.

article News story: East London teenagers present 100 years of medical history
4, February , 2014

Young Londoners have travelled back in time some 100 years to discover how people lived, worked and died in the East End and what impact the area’s medical history has on the current generation.

article News story: Universities announce rare disease research agreement with Pfizer Inc.
9, May , 2014

Today, GMEC, the Global Medical Excellence Cluster, announced a five year collaborative agreement with Pfizer Inc. that provides a framework for the research and development of new and innovative medicines for rare diseases.

article News story: Two thirds of women are not taking folic acid supplements before pregnancy to prevent spina bifida
19, February , 2014

New research from Queen Mary University of London reveals less than 1 in 3 women have taken folic acid supplements before pregnancy to prevent spina bifida and other birth defects of the brain, spine, or spinal cord (neural tube defects). This is despite research from 1991 showing that such conditions could be prevented in most cases by increasing the intake of the B-vitamin folic acid before pregnancy.

article News story: Youth, wealth and education found to be risk factors for violent radicalisation
19, March , 2014

New research from Queen Mary University of London has found youth, wealth, and being in full-time education to be risk factors associated with violent radicalisation. Contrary to popular views – religious practice, health and social inequalities, discrimination, and political engagement showed no links.

article News story: Queen Mary University of London to host Genomics England on campus during delivery of 100,000 Genomes Project
22, April , 2014

Genomics England – the company set up by the Department of Health to deliver the Government’s 100,000 Genomes Project – will move into newly refurbished headquarters on Queen Mary University of London’s Charterhouse Square campus from 21 April 2014.

article News story: Study reveals unexpected cell hijack method in pancreatic cancer
11, February , 2014

Pancreatic stellate cells, which normally aid tissue repair, unwittingly help pancreatic cancer grow and spread in a method of ‘cell hijack’ only seen before in brain and breast cancer, according to new research from Queen Mary University of London.

article News story: Queen Mary University of London awarded £24m from MRC to support the 100,000 Genomes Project
1, August , 2014

Queen Mary University of London (QMUL) has been awarded £24m from the MRC to support Genomics England in the delivery of the Government's 100,000 Genomes Project. The award will go directly towards providing cutting-edge Genomics Medicine Data Architecture.

article News story: The UK’s first new dental school and hospital for 40 years opens today
12, June , 2014

Patients and students in London’s East End are set to benefit as the UK’s first new dental school and hospital in nearly 40 years – the £78m Royal London Dental Hospital – officially opens its doors today.

article News story: Care Bill changes required to secure public trust and the availability of information for public health research
1, May , 2014

Writing in The Lancet today (Friday 2 May 2014), Allyson Pollock, Professor of Public Health Research and Policy and Peter Roderick, Barrister and Senior Research Fellow at Queen Mary University of London, call for crucial new amendments to the Care Bill in order to restore public trust in the use of patients’ data and to secure the on-going availability of genuinely anonymised information for public health research, planning and audit.

article News story: Summer sports challenges help fund the fight against cancer
10, July , 2014

Queen Mary University of London staff, students and alumni are helping fund the fight against cancer with a series of charity sports challenges this summer, including the British 10k Run, the London Triathlon and the Thames Path Challenge.

article News story: Dentistry at Queen Mary awarded for gender equality
1, May , 2014

Queen Mary University of London’s Institute of Dentistry has attained a Bronze award for the first time in the Athena SWAN scheme, which recognises excellence in recruiting and progressing women in Science, Technology, Engineering, Mathematics and Medicine (STEMM).

article News story: Queen Mary University of London launches ground-breaking asthma research centre
13, May , 2014

Queen Mary University of London (QMUL), along with colleagues from the University of Edinburgh and the charity Asthma UK, have today launched the UK’s first integrated Centre focused solely on improving the quality of life of people with asthma.

article News story: MRC awards announces £32 million towards improving data research
6, February , 2014

Queen Mary University of London, in partnership with UCL, London School of Hygiene and Tropical Medicine, the Francis Crick Institute, Wellcome Trust Sanger Institute and the European Bioinformatics Institute, has been awarded nearly £9 million by the Medical Research Council (MRC) to improve capability, capacity, training and capital infrastructure in medical bioinformatics. 

article News story: New study investigating impact of asthma on school children launches today
25, June , 2014

Asthma affects one in 11 children and young people in the UK. On average, this is two children in every classroom.  Today scientists in East London are launching a new study to measure the impact asthma has on school children, with the aim of improving school life for those with asthma.

article News story: Scientists discover treatment breakthrough for advanced bladder cancer
27, November , 2014

Scientists from Queen Mary University of London's Barts Cancer Institute have made a breakthrough in developing a new therapy for advanced bladder cancer – for which there have been no major treatment advances in the past 30 years.

article News story: New discovery on Giant Cell Arteritis sheds light on cause
17, January , 2014

New research from Queen Mary University of London has revealed – for the first time – how the condition Giant Cell Arteritis (GCA) may be caused by a certain group of white blood cells called ‘neutrophils’. GCA (also known as temporal arteritis) is a condition which causes severe inflammation in the blood vessels and primarily affects the elderly.

article News story: Armed virus shows promise as treatment for pancreatic cancer
23, December , 2014

A new combination of two different approaches – virotherapy and immunotherapy - is showing “great promise” as a treatment for pancreatic cancer, according to new research from QMUL.

article News story: Vitamin D reduces lung disease flare-ups by over 40%
2, December , 2014

Vitamin D supplements can reduce COPD lung disease flare-ups by over 40% in patients with a vitamin D deficiency – according to new research from Queen Mary University of London.

article News story: New evidence reveals tamoxifen reduces breast cancer rates by nearly a third for 20 years
11, December , 2014

The preventive effect of breast cancer drug ‘tamoxifen’ remains virtually constant for at least 20 years – with rates reduced by around 30 per cent – new analysis published in The Lancet Oncology reveals.  

article News story: QMUL’s Dr Neha Pathak wins Cosmopolitan Magazine’s Ultimate Women Award
4, December , 2014

Dr Neha Pathak, an Academic Clinical Fellow from Queen Mary University of London, was last night awarded the ‘Ultimate Game Changer’ prize at the Cosmopolitan Ultimate Women Awards.

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