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Clinical Microbiology: Diagnosis and Management of Human Disease and Control of Hospital Infection (ICM7036)

Module convener                          

Michele Branscombe, m.branscombe@qmul.ac.uk 

Other Key Staff:                                              

Professor Mike Millar (Control of Hospital Acquired Infection), Michael.Millar@bartsandthelondon.nhs.uk

Throughout this module students will study microbial infections of humans. The clinical presentation, laboratory diagnosis, antimicrobial therapy and infection control issues of the microbial infections are explored both theoretically and practically. The infections are studied by organ system e.g. respiratory tract, gastrointestinal tract and also by looking at specialist patient groups e.g. the immunocompromised, paediatrics.
Students also study the surveillance, legislation and methods of control of hospital acquired infection.

The module aims to provide:

  • An in depth study of the aetiology, presentation and antimicrobial therapy of infectious disease by organ system e.g. respiratory tract, gastrointestinal tract.
  • An in depth study of the aetiology, presentation and antimicrobial therapy of infectious disease in specialist patient groups e.g. the immunocompromised, infections during pregnancy
  • Practical experience of the laboratory investigation of infections including point of care testing.
  • A knowledge of surveillance of hospital acquired infection
  • An understanding of methods of transmission of hospital acquired infection and appropriate measures to control hospital acquired infection.
  • An understanding of the legislation relating to hospital acquired infection.

At the end of this module students will be able to:

  • Understand the diversity of infectious agents causing systemic disease and be able to apply their knowledge to assist in the diagnosis and therapy of infectious disease.
  • Demonstrate that they are aware that specialist patient groups may present with unique clinical situations which require special consideration.
  • Demonstrate the practical skills in a clinical laboratory to investigate clinical samples to guide diagnosis and therapy of the patient.
  • Participate in routine surveillance for hospital acquired infection
  • Appreciate methods of transmission of hospital acquired infection and be able to instigate appropriate measures to control hospital acquired infection. Students will be equipped to work within a multidisciplinary infection control team and to relate to other professionals within the team.
  • Demonstrate an understanding of the legislation relating to hospital acquired infection.

Students are expected to develop a strong basic background from text books but this must be supplemented by research in current scientific literature.

Suggested background texts include:

Bannister et al: Infection, Microbiology and Management
Mandell et al: Principles and Practices of Infectious Diseases

British National Formulary

Wilson: Infection control in clinical practice
Hawker et al: Communicable disease control handbook

Suggested journals include:

The Lancet Infectious Diseases
Journal of Infection
Current Opinions in Infectious Disease

Spot examination

This is a written examination answering short questions about the laboratory diagnosis of infection and longer questions about interpretation of laboratory results.
Type of assessment: Coursework
Duration: 2 hours
Percentage weighting in module:15%

Midmodule examination

Type of assessment: Coursework
Duration: 60 minutes
Percentage weighting in module: 15%

End of Module Examination

Type of assessment: Formal examination
Duration: 2 hours
Percentage weighting in module: 70%

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